Prognostic factors of recovery with medication in patients with taste disorders

被引:2
|
作者
Nomura, Yasuyuki [1 ]
Toi, Teruo [1 ]
Ikeda, Minoru [2 ]
Ikeda, Atsuo [1 ]
Tanaka, Makoto [1 ]
Oshima, Takeshi [1 ]
机构
[1] Nihon Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Tokyo, Japan
[2] Ikeda ENT Clin, Tokyo, Japan
来源
PLOS ONE | 2020年 / 15卷 / 10期
关键词
DOUBLE-BLIND; ZINC-DEFICIENCY; HYPOGEUSIA; SMELL; POLAPREZINC; RECEPTOR; SULFATE; TRIAL; AGE;
D O I
10.1371/journal.pone.0237270
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objectives We aimed to elucidate the prognostic factors of the patients with taste disorders who were treated with popular and common medication in Japan. Materials and methods A retrospective study on the medical charts of a total of 255 patients with taste disorders who were treated primarily with oral medication including a zinc agent. Results The factors below were significantly linked with poor prognosis: 1) male gender, 2) taste disorders that began 3 months before starting treatment and 3) a severe taste disorder grade at the initial visit. Conclusions We have concluded that the prognosis for the patients with taste disorders who were treated by popular and standard medication therapy in Japan recently was significantly linked to gender, the period of 3 months before starting the treatment and the severity of the disorder at the time of diagnosis. In addition, we recognized some limitations we should resolve in further research including a method of measuring "umami" and so on.
引用
收藏
页数:9
相关论文
共 50 条
  • [31] Drug-induced taste disorders
    Naik, B. Sadananda
    Shetty, Nagaraj
    Maben, E. V. S.
    EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2010, 21 (03) : 240 - 243
  • [32] A study about the frequency of taste disorders
    Welge-Luessen, Antje
    Doerig, Patrick
    Wolfensberger, Markus
    Krone, Franziska
    Hummel, Thomas
    JOURNAL OF NEUROLOGY, 2011, 258 (03) : 386 - 392
  • [33] Factors associated with gustatory threshold for salty taste in peritoneal dialysis patients
    Torigoe, Kenta
    Obata, Yoko
    Morimoto, Shimpei
    Torigoe, Miki
    Oka, Satoru
    Uramatsu, Tadashi
    Mukae, Hiroshi
    Nishino, Tomoya
    RENAL REPLACEMENT THERAPY, 2019, 5 (01)
  • [34] Smell and taste disorders in polyneuropathy: a prospective study of chemosensory disorders
    Heckmann, J. G.
    Hoecherl, C.
    Duetsch, M.
    Lang, C.
    Schwab, S.
    Hummel, T.
    ACTA NEUROLOGICA SCANDINAVICA, 2009, 120 (04): : 258 - 263
  • [35] Prognostic Factors in Hantavirus Infections
    Kaya, Selcuk
    MIKROBIYOLOJI BULTENI, 2014, 48 (01): : 179 - 187
  • [36] Effect of trifluridine/tipiracil in patients treated in RECOURSE by prognostic factors at baseline: an exploratory analysis
    Tabernero, Josep
    Argiles, Guillem
    Sobrero, Alberto F.
    Borg, Christophe
    Ohtsu, Atsushi
    Mayer, Robert J.
    Vidot, Loick
    Vera, Shanti R. Moreno
    Van Cutsem, Eric
    ESMO OPEN, 2020, 5 (04)
  • [37] EVALUATION OF TREATMENT OUTCOMES AND PROGNOSTIC FACTORS FOR IDIOPATHIC PERIPHERAL FACIAL PARALYSIS IN GERIATRIC PATIENTS
    Dogan, Ersoy
    Olgun, Yuksel
    Erdag, Taner Kemal
    TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI, 2013, 16 (04): : 421 - 426
  • [38] Reconsideration of Clinical and Histopathological Prognostic Factors in Breast Cancer Patients: A Single Center Experience
    Tanriverdi, Ozgur
    Meydan, Nezih
    Barutca, Sabri
    ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (02) : 807 - 812
  • [39] A Review of Zinc-L-Carnosine and Its Positive Effects on Oral Mucositis, Taste Disorders, and Gastrointestinal Disorders
    Hewlings, Susan
    Kalman, Douglas
    NUTRIENTS, 2020, 12 (03)
  • [40] Multiple myeloma in elderly patients: prognostic factors and outcome
    Anagnostopoulos, A
    Gika, D
    Symeonidis, A
    Zervas, K
    Pouli, A
    Repoussis, P
    Grigoraki, V
    Anagnostopoulos, N
    Economopoulos, T
    Maniatis, A
    Dimopoulos, MA
    EUROPEAN JOURNAL OF HAEMATOLOGY, 2005, 75 (05) : 370 - 375