Prognostic factors of recovery with medication in patients with taste disorders

被引:2
|
作者
Nomura, Yasuyuki [1 ]
Toi, Teruo [1 ]
Ikeda, Minoru [2 ]
Ikeda, Atsuo [1 ]
Tanaka, Makoto [1 ]
Oshima, Takeshi [1 ]
机构
[1] Nihon Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Tokyo, Japan
[2] Ikeda ENT Clin, Tokyo, Japan
来源
PLOS ONE | 2020年 / 15卷 / 10期
关键词
DOUBLE-BLIND; ZINC-DEFICIENCY; HYPOGEUSIA; SMELL; POLAPREZINC; RECEPTOR; SULFATE; TRIAL; AGE;
D O I
10.1371/journal.pone.0237270
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objectives We aimed to elucidate the prognostic factors of the patients with taste disorders who were treated with popular and common medication in Japan. Materials and methods A retrospective study on the medical charts of a total of 255 patients with taste disorders who were treated primarily with oral medication including a zinc agent. Results The factors below were significantly linked with poor prognosis: 1) male gender, 2) taste disorders that began 3 months before starting treatment and 3) a severe taste disorder grade at the initial visit. Conclusions We have concluded that the prognosis for the patients with taste disorders who were treated by popular and standard medication therapy in Japan recently was significantly linked to gender, the period of 3 months before starting the treatment and the severity of the disorder at the time of diagnosis. In addition, we recognized some limitations we should resolve in further research including a method of measuring "umami" and so on.
引用
收藏
页数:9
相关论文
共 50 条
  • [21] Influence of taste disorders on dietary behaviors in cancer patients under chemotherapy
    Sanchez-Lara, Karla
    Sosa-Sanchez, Ricardo
    Green-Renner, Dan
    Rodriguez, Cindy
    Laviano, Alessandro
    Motola-Kuba, Daniel
    Arrieta, Oscar
    NUTRITION JOURNAL, 2010, 9
  • [22] Multiple Types of Taste Disorders among Patients with COVID-19
    Nanjo, Yuta
    Okuma, Tomoko
    Kuroda, Yumi
    Hayakawa, Eri
    Shibayama, Kohei
    Akimoto, Takashi
    Murashima, Ryoko
    Kanamori, Koichiro
    Tsutsumi, Takeo
    Suzuki, Yohei
    Namba, Yukiko
    Makino, Fumihiko
    Nagashima, Osamu
    Sasaki, Shinichi
    Takahashi, Kazuhisa
    INTERNAL MEDICINE, 2021, 61 (14) : 2127 - 2134
  • [23] How to Manage Taste Disorders
    Julien Wen Hsieh
    Dimitrios Daskalou
    Sonia Macario
    Francois Voruz
    Basile Nicolas Landis
    Current Otorhinolaryngology Reports, 2022, 10 : 385 - 392
  • [24] Taste disorders - Ein Update
    Landis, B. N.
    Just, T.
    HNO, 2010, 58 (07) : 650 - 655
  • [25] Prognostic factors in patients with recurrent ovarian cancer treated with radiation therapy
    Kosaka, Nobuaki
    Hasegawa, Kiyoshi
    Kiuchi, Kaori
    Motegi, Emi
    Ejima, Yasuo
    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2021, 42 (02) : 311 - 318
  • [26] Recovery Over Time and Prognostic Factors in Treated Patients with Post-Infectious Olfactory Dysfunction: A Retrospective Study
    Ogawa, Takao
    Nakamura, Keigo
    Yamamoto, Sayuri
    Tojima, Ichiro
    Shimizu, Takeshi
    ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2020, 129 (10) : 977 - 982
  • [27] Prognostic Factors of Motor Recovery after Stereotactic Evacuation of Intracerebral Hematoma
    Enatsu, Rei
    Asahi, Minoru
    Matsumoto, Masato
    Hirai, Osamu
    TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 2012, 227 (01) : 63 - 67
  • [28] Taste disorders following cancer treatment: report of a case series
    Epstein, Joel B.
    de Andrade e Silva, Safira Marques
    Epstein, Geena L.
    Santos Leal, Jorge Henrique
    Barasch, Andrei
    Smutzer, Gregory
    SUPPORTIVE CARE IN CANCER, 2019, 27 (12) : 4587 - 4595
  • [29] Prognostic factors in refractory metastatic colorectal cancer patients treated with Trifluridine/Tipiracil
    Koper, Agnieszka
    Wilenski, Slawomir
    Sledzinska, Paulina
    Bebyn, Marek
    Koper, Krzysztof
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023, 149 (12) : 10867 - 10877
  • [30] Future perspectives in smell and taste disorders
    Lacroix, J. -S.
    Landis, B. N.
    B-ENT, 2009, : 133 - 136