Prognostic factors of recovery with medication in patients with taste disorders

被引:2
|
作者
Nomura, Yasuyuki [1 ]
Toi, Teruo [1 ]
Ikeda, Minoru [2 ]
Ikeda, Atsuo [1 ]
Tanaka, Makoto [1 ]
Oshima, Takeshi [1 ]
机构
[1] Nihon Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Tokyo, Japan
[2] Ikeda ENT Clin, Tokyo, Japan
来源
PLOS ONE | 2020年 / 15卷 / 10期
关键词
DOUBLE-BLIND; ZINC-DEFICIENCY; HYPOGEUSIA; SMELL; POLAPREZINC; RECEPTOR; SULFATE; TRIAL; AGE;
D O I
10.1371/journal.pone.0237270
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objectives We aimed to elucidate the prognostic factors of the patients with taste disorders who were treated with popular and common medication in Japan. Materials and methods A retrospective study on the medical charts of a total of 255 patients with taste disorders who were treated primarily with oral medication including a zinc agent. Results The factors below were significantly linked with poor prognosis: 1) male gender, 2) taste disorders that began 3 months before starting treatment and 3) a severe taste disorder grade at the initial visit. Conclusions We have concluded that the prognosis for the patients with taste disorders who were treated by popular and standard medication therapy in Japan recently was significantly linked to gender, the period of 3 months before starting the treatment and the severity of the disorder at the time of diagnosis. In addition, we recognized some limitations we should resolve in further research including a method of measuring "umami" and so on.
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页数:9
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