A direct synthesis of aflatoxin M2

被引：11
作者：
Kraus, GA [1 ]
Wang, XM [1 ]
机构：
[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 49期
关键词：
D O I：
10.1016/S0040-4039(99)01820-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A six-step synthesis of aflatoxin M-2 Starting from 1,3,5-trimethoxybenzene is described. The key step is the addition of dichloromethyllithium. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8513 / 8514
页数：2
相关论文
共 11 条
  • [1] BUCHI G, 1981, J AM CHEM SOC, V103, P3497, DOI 10.1021/ja00402a039
  • [2] SYNTHESES OF TETRAHYDROFURO[2,3-B]BENZOFURANS - A SYNTHESIS OF (H-AFLATOXIN-B2
    CASTELLINO, AJ
    RAPOPORT, H
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (07) : 1006 - 1011
  • [3] CATHEY CG, 1994, J DAIRY SCI, V75, P1223
  • [4] DEVELOPMENT OF AN IMMUNOAFFINITY COLUMN AND AN INDIRECT IMMUNOASSAY WITH A BIOTIN STREPTAVIDIN DETECTION SYSTEM FOR AFLATOXIN M(1) IN MILK
    DEBOEVERE, C
    VANPETEGHEM, C
    [J]. ANALYTICA CHIMICA ACTA, 1993, 275 (1-2) : 341 - 345
  • [5] THE REGIOSPECIFIC PARA-DEIODINATION OF 2,4-DI-IODO PHENOLS - A NEW SYNTHESIS OF AFLATOXIN-B2
    HORNE, S
    WEERATUNGA, G
    RODRIGO, R
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (01) : 39 - 41
  • [6] AN APPROACH TO AFLATOXINS USING TYPE-II PHOTOCYCLIZATION REACTIONS
    KRAUS, GA
    THOMAS, PJ
    SCHWINDEN, MD
    [J]. TETRAHEDRON LETTERS, 1990, 31 (13) : 1819 - 1822
  • [7] A DIRECT SYNTHESIS OF RACEMIC DEMETHOXYAFLATOXIN-B2
    KRAUS, GA
    JOHNSTON, BE
    APPLEGATE, JM
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (19) : 5688 - 5691
  • [8] Kraus GA, 1999, SYNLETT, P1395
  • [9] Schuda P.F., 1980, TOP CURR CHEM, V91, P75, DOI 10.1007/3-540-09827-5_3
  • [10] VANKAR YD, 1985, J CHEM RES-S, P232
12