Plant NLRs get by with a little help from their friends

被引:70
作者
Feehan, Joanna M. [1 ]
Castel, Baptiste [1 ,3 ]
Bentham, Adam R. [2 ]
Jones, Jonathan D. G. [1 ]
机构
[1] Univ East Anglia, Sainsbury Lab, Norwich Res Pk, Norwich, Norfolk, England
[2] Norwich Res Pk, John Innes Ctr, Norwich, Norfolk, England
[3] Natl Univ Singapore, Dept Biol Sci, Singapore, Singapore
基金
英国生物技术与生命科学研究理事会;
关键词
NB-LRR PROTEIN; DISEASE RESISTANCE; CELL-DEATH; IMMUNE RECEPTORS; MILDEW RESISTANCE; TIR DOMAINS; GENES; RECOGNITION; ARABIDOPSIS; PATHWAYS;
D O I
10.1016/j.pbi.2020.04.006
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Many plant NLR (nucleotide-binding, leucine-rich repeat) immune receptors require other NLRs for their function. In pairs of chromosomally adjacent sensor/helper NLRs, the sensor typically carries an integrated domain (ID) that mimics the authentic target of a pathogen effector. The RPW8-NLR Glade supports the function of many diverse plant NLRs, particularly those with a TIR N-terminal domain, in concert with a family of EP-domain containing signalling partners. The NRC Glade of NLRs are required for the function of many unlinked sensor NLRs in Solanaceous plants. We evaluate recent advances in paired NLR biology in the context of the structure and possible mechanisms of the first defined plant inflammasome containing ZAR1.
引用
收藏
页码:99 / 108
页数:10
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