Subclinical Cushing Syndrome: A Review

被引：13

作者：

Starker, Lee F. ^{[1
]}

Kunstman, John W. ^{[1
]}

Carling, Tobias ^{[1
,2
]}

机构：

[1] Yale Univ, Sch Med, Dept Surg, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Yale Endocrine Neoplasia Lab, New Haven, CT 06520 USA

来源：

SURGICAL CLINICS OF NORTH AMERICA | 2014年 / 94卷 / 03期

关键词：

Subclinical Cushing syndrome; Adrenal incidentalomas; Dexamethasone-suppressive testing; Corticotropin; DISCOVERED ADRENAL MASSES; URINARY FREE CORTISOL; CLINICAL-PRACTICE GUIDELINE; SALIVARY CORTISOL; DEXAMETHASONE SUPPRESSION; INCIDENTALOMAS; DIAGNOSIS; MANAGEMENT; HYPERCORTISOLISM; ADENOMAS;

D O I：

10.1016/j.suc.2014.02.008

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Owing to its diagnostic challenges, subclinical Cushing syndrome (SCS) is likely to be highly underdiagnosed and undertreated, and the overall incidence may be as high as 5% to 20% in patients with adrenal incidentalomas. The diagnosis can be established by a systematic and thorough biochemical evaluation. SCS has been associated with significant morbidity, which at least partly may be reversed by surgery. Given the low rates of complications and the possibility to reverse the detrimental effects of elevated cortisol secretion, minimally invasive adrenalectomy is recommended for patients with biochemically proven or suspected SCS who are appropriate surgical candidates.

引用

页码：657 / +

页数：13

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