Bacterial Infection as a Cause of Infertility in Humans

被引:0
作者
Sleha, Radek [1 ,2 ]
Bostikova, Vanda [1 ]
Salavec, Miloslav [3 ]
Mosio, Petra [2 ]
Kusakova, Eva [2 ]
Kukla, Rudolf [2 ]
Mazurova, Jaroslava [2 ]
Splino, Miroslav [1 ]
机构
[1] Univ Obrany, Fak Vojenskeho Zdravotnictvi, Katedra Epidemiol, Hradec Kralove 50001, Czech Republic
[2] Univ Pardubice, Fak Chem Technol, Katedra Biol & Biochem Ved, Pardubice, Czech Republic
[3] Klin & Katedra Nemoci Koznich & Pohlavnich FN & L, Hradec Kralove, Czech Republic
来源
EPIDEMIOLOGIE MIKROBIOLOGIE IMUNOLOGIE | 2013年 / 62卷 / 01期
关键词
urogenital infections; infertility; Neisseria gonorrhoeae; Chlamydia trachomatis; Mycoplasma sp; Ureaplasma sp; Gardnerella vaginalis; GARDNERELLA-VAGINALIS; CHLAMYDIA-TRACHOMATIS; TRACT INFECTIONS; WOMEN; PREVALENCE; IMPACT; TUBERCULOSIS;
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Microorganisms which are present in the human urogenital tract may be involved in the development of inflammatory changes negatively affecting the genitals in both men and women. Pathological conditions due to inflammatory alterations may result in complete loss of fertility. Infections of the urogenital tract are responsible for 15% of all cases of infertility in couples. Negative impact on the human reproduction is mainly caused by direct damage to the genital tract mucosa by metabolic products of microorganisms or by induction of pro-inflammatory responses of the body. Another mechanism is indirect impact of microorganisms on the genital function. Moreover, the effect of bacteria on spermatogenesis and semen quality is important in men. Infections mainly caused by Chlamydia trachomatis or Neisseria gonorrhoeae represent the greatest risk in terms of permanent consequences for human reproduction. As for other sexually transmitted disorders, such as infections caused by Gardnerella vaginalis, urogenital mycoplasmas or ureaplasmas, the link between infection and infertility has been intensively researched.
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页码:26 / 32
页数:7
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