Synthesis and Cytotoxicity of N-(3,4-Dimethoxyphenyl)Ethylamides of N-Benzoyl-α-Amino Acids

被引:2
作者
Tukhtaev, D. B. [1 ]
Saidov, A. Sh [1 ]
Alimova, M. [1 ]
Terent'eva, E. O. [2 ]
Khashirnova, Z. S. [2 ]
Azimova, Sh S. [2 ]
Vinogradova, V., I [2 ]
机构
[1] Samarkand State Univ, Samarkand, Uzbekistan
[2] Acad Sci Uzbek, SYu Yunusov Inst Chem Plant Subst, Tashkent, Uzbekistan
关键词
alpha-amino acids; Schotten-Baumann method; N-benzoyl alpha-amino acid derivatives; homoveratrylamine; amides; cytotoxicity; DERIVATIVES;
D O I
10.1007/s10600-019-02782-9
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Amides were synthesized from N-benzoyl aliphatic alpha-amino acids and homoveratrylamine and screened for cytotoxicity.
引用
收藏
页码:700 / 704
页数:5
相关论文
共 21 条
[1]  
AGABABYAN AG, 1984, KHIM FARM ZH+, V18, P691
[2]  
Anikina L. V., 2002, Khimiko-Farmatsevticheskii Zhurnal, V36, P19
[3]  
Butler M., 2014, NAT PROD REP, V1-2, p[33, 475]
[4]  
Gorbunov A. A., 2001, NITROGENOUS HETEROCY, V2, P83
[5]   Substituent-dependent negative hyperconjugation in 2-aryl-1,3-N,N-heterocycles.: Fine-tuned anomeric effect? [J].
Hetényi, AN ;
Martinek, TA ;
Lázár, L ;
Zalán, Z ;
Fülöp, F .
JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (14) :5705-5712
[6]   A SIMPLE PREPARATION OF AMIDES FROM ACIDS AND AMINES BY HEATING OF THEIR MIXTURE [J].
JURSIC, BS ;
ZDRAVKOVSKI, Z .
SYNTHETIC COMMUNICATIONS, 1993, 23 (19) :2761-2770
[7]   Preparation of N-acyl derivatives of amino acids from acyl chlorides and amino acids in the presence of cationic surfactants.: A variation of the Schotten-Baumann method of benzoylation of amino acids [J].
Jursic, BS ;
Neumann, D .
SYNTHETIC COMMUNICATIONS, 2001, 31 (04) :555-564
[8]  
Kapoor A., 2016, PHARM LETT, V8, P135
[9]  
Kazaryan S. A., 1995, Khimiko-Farmatsevticheskii Zhurnal, V29, P11
[10]   Catalytic amide formation from non-activated carboxylic acids and amines [J].
Lundberg, Helena ;
Tinnis, Fredrik ;
Selander, Nicklas ;
Adolfsson, Hans .
CHEMICAL SOCIETY REVIEWS, 2014, 43 (08) :2714-2742