R-spondin1 tips the balance in sex determination

被引:35
作者
Capel, Blanche [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Cell Biol, Durham, NC 27710 USA
关键词
D O I
10.1038/ng1106-1233
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Female-to-male sex reversal is an extremely rare and puzzling phenomenon. A new study identifies mutations in the gene encoding R-spondin1 in XX sex-reversed individuals and suggests that antagonistic pathways in the bipotential gonad regulate sex determination.
引用
收藏
页码:1233 / 1234
页数:3
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