New approach to indole alkaloids based on the intramolecular Pauson-Khand reaction

被引：33
|
作者：
Pérez-Serrano, L [1 ]
Domínguez, G [1 ]
Pérez-Castells, J [1 ]
机构：
[1] Univ San Pablo, CEU, Fac Ciencias Expt & Salud, Dept Quim, Madrid 28668, Spain
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 16期
关键词：
D O I：
10.1021/jo049309h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of indoles bearing alkenyl and alkynyl moieties in different positions of the nucleus is described. These compounds are used as substrates for the intermolecular Pauson-Ehand reaction leading to tetracyclic cyclopentenones with formation of additional five- to seven-membered rings. Products are related to alkaloids such as mitosenes, clausines, ergotamines, or apogeissochizines.
引用
收藏
页码：5413 / 5418
页数：6
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