Complete resolution of posttransplant lymphoproliferative disorder (diffuse large B-cell lymphoma) with reduction of immunosuppressive therapy

被引:3
|
作者
Ryu, HJ
Hahn, JS
Kim, YS
Park, K
Yang, WI
Lee, JD
机构
[1] Yonsei Univ, Coll Med, Dept Internal Med, Seoul 120752, South Korea
[2] Yonsei Univ, Coll Med, Dept Surg, Seoul 120752, South Korea
[3] Yonsei Univ, Coll Med, Dept Pathol, Seoul 120752, South Korea
[4] Yonsei Univ, Coll Med, Dept Radiol, Seoul 120752, South Korea
关键词
PTLD; immunosuppression; reduction; resolution;
D O I
10.3349/ymj.2004.45.3.527
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation. PTLD is the disorder arising from the combined effects of Epstein-Barr virus associated lymphoid proliferation with the disruption of the normal immune control by the cytotoxic T cells. The treatment for PTLD is one of the most controversial topics in solid organ transplantation. It is well known that the initial management of PTLD is a reduction of immunosuppression. Early diagnosis and the early reduction in immunosuppression are essential even for monomorphic lymphoma. We report here on a case of the complete resolution of PTLD (diffuse large B cell lymphoma) which occurred after a drastic reduction of immunosuppression in a renal transplant recipient.
引用
收藏
页码:527 / 532
页数:6
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