N-(Hetero)aryl-2-imidazolines: an emerging privileged motif for contemporary drug design

被引：16
作者：
Krasavin, Mikhail [1 ]
机构：
[1] St Petersburg State Univ, Inst Chem, 26 Univ Skii Ave, Petrodvorets 198504, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2017年 / 53卷 / 03期
基金：
俄罗斯科学基金会;
关键词：
cyclodehydration; imidazoline N-arylation; lead-like compounds; privileged structures; CATALYZED N-ARYLATION; ONE-POT SYNTHESIS; CYCLOOXYGENASE-2; INHIBITORS; RECEPTOR MODULATORS; KINASE INHIBITORS; RING EXPANSION; DISCOVERY; 2-IMIDAZOLINES; DERIVATIVES; AMIDINES;
D O I：
10.1007/s10593-017-2047-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The diverse biological activities of compounds containing N-(hetero)aryl-2-imidazoline moiety and methods to construct them are comprehensively reviewed for the first time. This intriguing non-flat, cyclic amidine motif clearly represents an emerging privileged structure.
引用
收藏
页码：240 / 255
页数：16
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