Oxygen transport and utilisation during exercise in cystic fibrosis: contributors to exercise intolerance

被引:7
作者
Saynor, Zoe L. [1 ]
Gruet, Mathieu [2 ]
Rodriguez-Miguelez, Paula [3 ]
Harris, Ryan A. [4 ]
机构
[1] Univ Portsmouth, Fac Sci & Hlth, Sch Sport Hlth & Exercise Sci, Portsmouth PO12ER, Hants, England
[2] Toulon Univ, Lab Impact Phys Act Hlth IAPS, Toulon, France
[3] Virginia Commonwealth Univ, Coll Humanities & Sci, Dept Kinesiol & Hlth Sci, Richmond, VA USA
[4] Augusta Univ, Dept Med, Georgia Prevent Inst, Augusta, GA USA
关键词
cystic fibrosis; exercise intolerance; haemodynamics; O-2; delivery; utilisation; TRANSMEMBRANE CONDUCTANCE REGULATOR; CHLORIDE CHANNEL; HEART INVOLVEMENT; UPTAKE KINETICS; YOUNG-PATIENTS; DYSFUNCTION; SILDENAFIL; ADULTS;
D O I
10.1113/EP088106
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
New Findings What is the topic of this review? This review highlights the central and peripheral mechanisms that alter oxygen transport and utilisation and thereby contribute to exercise limitation in people with cystic fibrosis, considering also viable therapeutic targets for intervention.
引用
收藏
页码:1979 / 1983
页数:5
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