Nanocrystalline MgAl2O4 as an efficient catalyst for one-pot synthesis of multisubstituted imidazoles under solvent-free conditions

被引:17
作者
Safari, Javad [1 ]
Akbari, Zahra [1 ]
Naseh, Simin [1 ]
机构
[1] Univ Kashan, Coll Chem, Dept Organ Chem, Organ Chem Res Lab, Kashan 8731751167, Iran
关键词
Nanocrystalline magnesium aluminate; Multi-component reactions; Solvent-free; 2,4,5-Trisubstituted imidazoles; 1,2,4,5-Tetrasubstituted imidazoles; HIGHLY SUBSTITUTED IMIDAZOLES; 2,4,5-TRISUBSTITUTED IMIDAZOLES; SYSTEM; CONDENSATION; ALDEHYDES; MILD;
D O I
10.1016/j.jscs.2012.10.012
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An efficient and eco-friendly procedure has been developed using nanocrystalline MgAl2O4 with specific surface area as catalyst for rapid and an improved synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions in excellent yields. The method has several benefits, such as shorter reaction time, recyclable catalyst and excellent yields. (C) 2012 Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:S250 / S255
页数:6
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