Suburban leptospirosis:: Atypical lymphocytosis and γ-δ T cell response

被引:11
作者
Barry, Michele
Wisnewski, Adam V.
Matthias, Michael A.
Inouye, Sharon K.
Vinetz, Joseph M.
机构
[1] Yale Univ, Sch Med, Dept Med, New Haven, CT 06520 USA
[2] Univ Calif San Diego, Sch Med, Dept Med, Div Infect Dis, San Diego, CA 92103 USA
[3] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02115 USA
[4] Hebrew Sr Life, Aging Brain Ctr, Boston, MA USA
关键词
D O I
10.1086/508537
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Leptospirosis is a zoonotic disease associated with a changing global epidemiology. Recently, an increased incidence of canine leptospirosis in the northeastern United States and Canada has been associated with increasing rates of infection among reservoir hosts, such as skunks, raccoons, and squirrels, that are common in suburban settings. We describe a case of leptospirosis that provides new insight into the epidemiology, diagnosis, and pathogenesis of this disease acquired in the suburban setting. Atypical lymphocytosis corresponded to an expansion of gamma-delta T cells in peripheral blood.
引用
收藏
页码:1304 / 1307
页数:4
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