Process Optimization of Ultrasonic Extraction of Puerarin Based on Support Vector Machine

In ultrasonic extraction technology, optimization of technical parameters often considers extraction medium only, without including ultrasonic parameters. This paper focuses on controlling the ultrasonic extraction process of puerarin, investigating the influence of ultrasonic parameters on extraction rate, and empirically analyzing the main components of Pueraria, i.e., isoflavone compounds. A method is presented combining orthogonal experimental design with a support vector machine and a predictive model is established for optimization of technical parameters. From the analysis with the predictivemodel, appropriate process parameters are achieved for higher extraction rate. With these parameters in the ultrasonic extraction of puerarin, the experimental result is satisfactory. This method is of significance to the study of extracting root-stock plant medicines. (C) 2014 Chemical Industry and Engineering Society of China, and Chemical Industry Press. All rights reserved.