Catalytic -Alkylation/Reduction of Ketones with Primary Alcohols To Furnish Secondary Alcohols

被引：18

作者：

Lundberg, Helena ^{[1
]}

Adolfsson, Hans ^{[1
]}

机构：

[1] Univ Stockholm, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden

来源：

SYNTHESIS-STUTTGART | 2016年 / 48卷 / 05期

基金：

瑞典研究理事会;

关键词：

alpha-alkylation; transfer hydrogenation; ketone; alcohol; catalysis; tandem process; ASYMMETRIC TRANSFER HYDROGENATION; ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; CHEMOSELECTIVE TRANSFER HYDROGENATION; DIRECT ALPHA-ALKYLATION; BORROWING HYDROGEN; REDOX ISOMERIZATION; ALLYLIC ALCOHOLS; AROMATIC KETONES; RUTHENIUM; REDUCTION;

D O I：

10.1055/s-0035-1561315

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The formation of secondary alcohol products via a tandem -alkylation/transfer hydrogenation of ketones with primary alcohols is a little explored reaction with unrealized potential for green synthesis. This review covers the current literature in the field, including asymmetric versions of the reaction, and outlines future possibilities and challenges for the methodology. 1 Introduction 2 Formation of Racemic Alcohols 3 Formation of Enantiomerically Enriched Alcohols 4 Conclusions

引用

页码：644 / 652

页数：9

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