CRISPR/Cas Powered Multiplexed Biosensing

被引：81

作者：

Bruch, Richard ^{[1
,2
]}

Urban, Gerald A. ^{[1
,3
]}

Dincer, Can ^{[1
,2
,4
]}

机构：

[1] Univ Freiburg, Dept Microsyst Engn IMTEK, Lab Sensors, D-79110 Freiburg, Germany

[2] Univ Freiburg, Freiburg Ctr Interact Mat & Bioinspired Technol F, D-79110 Freiburg, Germany

[3] Univ Freiburg, Freiburg Mat Res Ctr FMF, D-79104 Freiburg, Germany

[4] Imperial Coll London, Royal Sch Mines, Dept Bioengn, London SW7 2AZ, England

来源：

TRENDS IN BIOTECHNOLOGY | 2019年 / 37卷 / 08期

关键词：

Analytes - Biosensing - Point-of-care testing - Single specimen;

D O I：

10.1016/j.tibtech.2019.04.005

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Multiplexed CRISPR/Cas biosensing offers various possibilities for diagnosing different diseases by analyzing many analytes from one single specimen. However, in this relatively new field, nearly no multiplexing approaches exist, as many challenges need to be addressed. We discuss the reasons behind it and possible strategies to push the multiplexing level. © 2019 Elsevier Ltd

引用

页码：791 / 792

页数：2

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