Simple conjugated polymer nanoparticles as biological labels

被引：37

作者：

Green, Mark ^{[1
]}

Howes, Philip ^{[1
]}

Berry, Catherine ^{[2
]}

Argyros, Orestis ^{[3
,4
]}

Thanou, Maya ^{[3
,4
]}

机构：

[1] Kings Coll London, Dept Phys, Strand, London WC2R 2LS, England

[2] Univ Glasgow, Ctr Cell Engn, IBLS, Glasgow G12 8QQ, Lanark, Scotland

[3] Kings Coll London, Dept Pharm, London SE1 9NH, England

[4] Univ London Imperial Coll Sci Technol & Med, Genet Therapies Ctr, Dept Chem, London SW7 2AZ, England

来源：

PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES | 2009年 / 465卷 / 2109期

关键词：

nanoparticles; conjugated polymers; biological labelling; QUANTUM DOTS; OPTICAL-PROPERTIES; CYTOTOXICITY; MORPHOLOGY; CDSE;

D O I：

10.1098/rspa.2009.0181

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The use of nanoparticles in biology, especially in cellular imaging, is extremely promising and offers numerous advantages over existing organic dye systems. There are, however, constraints that need to be addressed before the use of such materials in mainstream clinical applications can be realized. One of the main concerns is the use of metal-containing particles that are potentially toxic or interfere with other diagnostic processes. Here, we present the use of simple conjugated polymer nanoparticles as alternative photostable cellular optical imaging agents.

引用

页码：2751 / 2759

页数：9

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