Using GeneWise in the Drosophila annotation experiment

被引：285

作者：

Birney, E ^{[1
]}

Durbin, R ^{[1
]}

机构：

[1] Sanger Ctr, Cambridge CB10 1SA, England

来源：

GENOME RESEARCH | 2000年 / 10卷 / 04期

关键词：

D O I：

10.1101/gr.10.4.547

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The GeneWise method For combining gene prediction and homology searches was applied to the 2.9-Mb region from Drosophila melanogaster. The results from the Genome Annotation Assessment Project (GASP) showed that GeneWise provided reasonably accurate gene predictions. Further investigation indicates that many of the incorrect gene predictions From GeneWise were due to transposons with valid protein-coding genes and the remaining cases are pseudogenes or possible annotation oversights.

引用

页码：547 / 548

页数：2

共 8 条

[1]

Bateman A, 2004, NUCLEIC ACIDS RES, V32, pD138, DOI [10.1093/nar/gkp985, 10.1093/nar/gkh121, 10.1093/nar/gkr1065]

[2] Prediction of complete gene structures in human genomic DNA [J].