Quality of life after palliative radiotherapy in bone metastases: A literature review

被引：54

作者：

McDonald, Rachel ^{[1
]}

Chow, Edward ^{[1
]}

Rowbottom, Leigha ^{[1
]}

Bedard, Gillian ^{[1
]}

Lam, Henry ^{[1
]}

Wong, Erin ^{[1
]}

Popovic, Marko ^{[1
]}

Pulenzas, Natalie ^{[1
]}

Tsao, May ^{[1
]}

机构：

[1] Univ Toronto, Sunnybrook Hlth Sci Ctr, Odette Canc Ctr, Rapid Response Radiotherapy Program,Dept Radiat O, Toronto, ON, Canada

来源：

JOURNAL OF BONE ONCOLOGY | 2015年 / 4卷 / 01期

关键词：

Quality of life; Radiation therapy; Bone metastases; Advanced cancer; HALF-BODY IRRADIATION; RADIATION-THERAPY; RANDOMIZED-TRIAL; CANCER-PATIENTS; PAIN RELIEF; DISEASE; WIDESPREAD;

D O I：

10.1016/j.jbo.2014.11.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: To investigate the quality of life (QOL) following palliative radiotherapy for painful bone metastases. Methods: A literature search was conducted in OvidSP Medline (1946-jan Week 4 2014), Embase (1947 Week 5 2014), and the Cochrane Central Register of Controlled Trials (Dec 2013) databases. The search was limited to English. Subject headings and keywords included 'palliative radiation', 'cancer palliative therapy', 'bone metastases', 'quality of life', and 'pain'. All studies (prospective or retrospective) reporting change in QOL before and after palliative radiotherapy for painful bone metastases were included. Results: Eighteen articles were selected from a total of 1730. The most commonly used tool to evaluate QOL was the Brief Pain Inventory. Seventeen studies collected data prospectively. An improvement in symptoms and functional interference scores following radiotherapy was observed in all studies. The difference in changes in QOL between responders and non responders was inconsistently reported. Conclusion: QOL improves in patients who respond to palliative radiotherapy for painful bone metastases. (C) 2014 The Authors. Published by Elsevier GmbH.

引用

页码：24 / 31

页数：8

共 25 条

[1] Assessment of Health-related Quality of Life with the European Organization for Research and Treatment of Cancer QLQ-C15-PAL after Palliative Radiotherapy of Bone Metastases [J].

Caissie, A. ;

Zeng, L. ;

Nguyen, J. ;

Zhang, L. ;

Jon, F. ;

Dennis, K. ;

Holden, L. ;

Culleton, S. ;

Koo, K. ;

Tsao, M. ;

Barnes, E. ;

Danjoux, C. ;

Sahgal, A. ;

Simmons, C. ;

Chow, E. .

CLINICAL ONCOLOGY, 2012, 24 (02) :125-133

[2] EORTC QLQ-C15-PAL quality of life scores in patients with advanced cancer referred for palliative radiotherapy [J].

Caissie, Amanda ;

Culleton, Shaelyn ;

Janet Nguyen ;

Zhang, Liying ;

Zeng, Liang ;

Holden, Lori ;

Dennis, Kristopher ;

Chan, Esther ;

Jon, Florencia ;

Tsao, May ;

Danjoux, Cyril ;

Sahgal, Arjun ;

Barnes, Elizabeth ;

Koo, Kaitlin ;

Chow, Edward .

SUPPORTIVE CARE IN CANCER, 2012, 20 (04) :841-848

[3] What goes up does not always come down: patterns of distress, physical and psychosocial morbidity in people with cancer over a one year period [J].

Carlson, Linda E. ;

Waller, Amy ;

Groff, Shannon L. ;

Giese-Davis, Janine ;

Bultz, Barry D. .

PSYCHO-ONCOLOGY, 2013, 22 (01) :168-176

[4]

Chow Edward, 2004, Support Cancer Ther, V1, P179, DOI 10.3816/SCT.2004.n.009

[5] UPDATE OF THE INTERNATIONAL CONSENSUS ON PALLIATIVE RADIOTHERAPY ENDPOINTS FOR FUTURE CLINICAL TRIALS IN BONE METASTASES [J].

Chow, Edward ;

Hoskin, Peter ;

Mitera, Gunita ;

Zeng, Liang ;

Lutz, Stephen ;

Roos, Daniel ;

Hahn, Carol ;

van der Linden, Yvette ;

Hartsell, William ;

Kumar, Eshwar .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2012, 82 (05) :1730-1737

[6] FUNCTIONAL INTERFERENCE CLUSTERS IN CANCER PATIENTS WITH BONE METASTASES: A SECONDARY ANALYSIS OF RTOG 9714 [J].

Chow, Edward ;

James, Jennifer ;

Barsevick, Andrea ;

Hartsell, William ;

Ratcliffe, Sarah ;

Scarantino, Charles ;

Ivker, Robert ;

Roach, Mack ;

Suh, John ;

Petersen, Ivy ;

Konski, Andre ;

Demas, William ;

Bruner, Deborah .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 76 (05) :1507-1511

[7] Radiotherapy for Pain [J].

Culleton, S. ;

Kwok, S. ;

Chow, E. .

CLINICAL ONCOLOGY, 2011, 23 (06) :399-406

[8] The rapid access palliative radiotherapy program: blueprint for initiation of a one-stop multidisciplinary bone metastases clinic [J].

Fairchild, A. ;

Pituskin, E. ;

Rose, B. ;

Ghosh, S. ;

Dutka, J. ;

Driga, A. ;

Tachynski, P. ;

Borschneck, J. ;

Gagnon, L. ;

MacDonnell, S. ;

Middleton, J. ;

Thavone, K. ;

Carstairs, S. ;

Brent, D. ;

Severin, D. .

SUPPORTIVE CARE IN CANCER, 2009, 17 (02) :163-170

[9] Pain relief and quality of life following radiotherapy for bone metastases: a randomised trial of two fractionation schedules [J].

Gaze, MN ;

Kelly, CG ;

Kerr, GR ;

Cull, A ;

Cowie, VJ ;

Gregor, A ;

Howard, GCW ;

Rodger, A .

RADIOTHERAPY AND ONCOLOGY, 1997, 45 (02) :109-116

[10] EVALUATION OF RADIATION-THERAPY FOR BONE METASTASES - PAIN RELIEF AND QUALITY OF LIFE [J].

GILBERT, HA ;

KAGAN, AR ;

NUSSBAUM, H ;

RAO, AR ;

SATZMAN, J ;

CHAN, P ;

ALLEN, B ;

FORSYTHE, A .

AMERICAN JOURNAL OF ROENTGENOLOGY, 1977, 129 (06) :1095-1096

← 1 2 3 →