BLUF: a novel FAD-binding domain involved in sensory transduction in microorganisms

被引：348

作者：

Gomelsky, M ^{[1
]}

Klug, G

机构：

[1] Univ Wyoming, Dept Mol Biol, Laramie, WY 82071 USA

[2] Univ Giessen, Inst Mikrobiol & Mol Biol, D-35392 Giessen, Germany

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2002年 / 27卷 / 10期

关键词：

D O I：

10.1016/S0968-0004(02)02181-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel FAD-binding domain, BLUE exemplified by the N-terminus of the AppA protein from Rhodobacter sphaeroides, is present in various proteins, primarily from Bacteria. The BLUF domain is involved in sensing blue-light (and possibly redox) using FAD and is similar to the flavin-binding PAS domains and cryptochromes. The predicted secondary structure reveals that the BLUF domain is a novel FAD-binding fold.

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收藏

页码：497 / 500

页数：4

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