Endothelial nitric oxide synthase phosphorylated at Ser116 is localized in nerve fibers of the rat glandulae palatinae

被引：5
作者：
Korkmaz, Y
Bloch, W
Addicks, K
Baumann, MA
Raab, WHM
机构：
[1] Univ Dusseldorf, Dept Operat & Prevent Dept & Endodont, D-40225 Dusseldorf, Germany
[2] German Sports Univ, Dept Mol & Cellulat Sports Med, Cologne, Germany
[3] Univ Cologne, Dept Anat 1, Cologne, Germany
[4] Univ Cologne, Dept Operat Dent & Periodontol, Cologne, Germany
来源：
NEUROSCIENCE LETTERS | 2004年 / 363卷 / 01期
关键词：
eNOS; eNOS phosphorylation at Ser(1177); eNOS phosphorylation at Ser(116); eNOS phosphorylation at Thr(495); peripheral nerve fibers;
D O I：
10.1016/j.neulet.2004.03.045
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
It is known that total endothelial nitric oxide synthase (eNOS) is localized in peripheral nerve fibers, but the existence of the phosphorylation site/s of eNOS in peripheral nerve fibers is unknown. In the perfusion-fixed and decalcified sections of rat palates, eNOS and eNOS phosphorylated at Ser(116) were identified in the nerve fibers of the glandulae palatinae. The localization of eNOS phosphorylated at Ser(1177) and Thr(495) in nerve fibers was undetectable. It is concluded that eNOS is phosphorylated at Ser(116) in nerve fibers of the glandulae palatinae under basal conditions. The basal Ser(1177) and Thr(495) phosphorylation of eNOS are missing in nerve fibers of the glandulae palatinae. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
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页码：54 / 57
页数：4
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