The Placenta in Toxicology. Part III: Pathologic Assessment of the Placenta

被引:13
作者
Cline, J. Mark [1 ]
Dixon, Darlene [2 ]
Ernerudh, Jan [3 ]
Faas, Marijke M. [4 ]
Goehner, Claudia [5 ]
Haeger, Jan-Dirk [6 ]
Markert, Udo R. [5 ]
Pfarrer, Christiane [6 ]
Svensson-Arvelund, Judit [3 ]
Buse, Eberhard [7 ]
机构
[1] Wake Forest Sch Med, Comparat Med Sect, Dept Pathol, Winston Salem, NC 27157 USA
[2] NIEHS, NTP, NTP Lab, Res Triangle Pk, NC 27709 USA
[3] Linkoping Univ, Fac Hlth Sci, Dept Clin & Expt Med, Linkoping, Sweden
[4] Univ Groningen, Univ Med Ctr Groningen, Dept Pathol & Med Biol, Div Med Biol, Groningen, Netherlands
[5] Univ Hosp Jena, Dept Obstet, Placenta Lab, Jena, Germany
[6] Univ Vet Med Hannover, Dept Anat, Hannover, Germany
[7] Covance Labs GmbH, Munster, Germany
关键词
macaca; mus; rodent pathology; primate pathology; placenta; toxicology; RAT PLACENTA; FETAL; PREGNANCY; MICE; EXPRESSION; MORPHOLOGY; GESTATION; MACAQUE; LESIONS; WEIGHT;
D O I
10.1177/0192623313482207
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
This short review is derived from the peer-reviewed literature and the experience and case materials of the authors. Brief illustrated summaries are presented on the gross and histologic normal anatomy of rodent and macaque placentas, including typical organ weights, with comments on differences from the human placenta. Common incidental findings, background lesions, and induced toxic lesions are addressed, and a recommended strategy for pathologic evaluation of placentas is provided.
引用
收藏
页码:339 / 344
页数:6
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