Non-Coding RNAs and Endometrial Cancer

被引：67

作者：

Vallone, Cristina ^{[1
]}

Rigon, Giuliano ^{[2
]}

Gulia, Caterina ^{[3
]}

Baffa, Alberto ^{[1
]}

Votino, Raffaella ^{[1
]}

Morosetti, Giulia ^{[1
]}

Zaami, Simona ^{[4
]}

Briganti, Vito ^{[3
]}

Catania, Francesco ^{[5
]}

Gaffi, Marco ^{[6
]}

Nucciotti, Roberto ^{[7
]}

Costantini, Fabio Massimo ^{[7
]}

Piergentili, Roberto ^{[8
]}

Putignani, Lorenza ^{[9
,10
]}

Signore, Fabrizio ^{[1
]}

机构：

[1] Usl Sud Est Toscana, Misericordia Hosp Grosseto, Dept Obstet & Gynaecol, I-58100 Grosseto, Italy

[2] San Camillo Forlanini Hosp, Dept Obstet & Gynaecol, I-00152 Rome, Italy

[3] San Camillo Forlanini Hosp, Dept Pediat Surg & Urol, I-00152 Rome, Italy

[4] Sapienza Univ Rome, Dept Anat Histol Forens & Orthoped Sci, UoFT, I-00185 Rome, Italy

[5] Usl Sud Est Toscana, Santa Maria Gruccia Hosp Valdarno, Dept Obstet & Gynaecol, I-52025 Montevarchi, Italy

[6] San Camillo Forlanini Hosp, Dept Urol, I-00152 Rome, Italy

[7] Usl Sud Est Toscana, Misericordia Hosp Grosseto, Dept Urol, I-58100 Grosseto, Italy

[8] Italian Natl Res Council, Inst Mol Biol & Pathol, I-00185 Rome, Italy

[9] Bambino Gesu Pediat Hosp, Unit Human Microbiome, IRCCS, I-00165 Rome, Italy

[10] Bambino Gesu Pediat Hosp, Unit Parasitol, IRCCS, I-00165 Rome, Italy

来源：

GENES | 2018年 / 9卷 / 04期

关键词：

endometrial cancer; epigenetics; non-coding RNA (ncRNA); long non-coding RNA (lncRNA); small non-coding RNA (small ncRNA); CELL-PROLIFERATION; PTEN EXPRESSION; PROMOTES; ROR; MIGRATION; INVASION; LNCRNA; TUMORIGENESIS; PROGRESSION; CARCINOMA;

D O I：

10.3390/genes9040187

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Non-coding RNAs (ncRNAs) are involved in the regulation of cell metabolism and neoplastic transformation. Recent studies have tried to clarify the significance of these information carriers in the genesis and progression of various cancers and their use as biomarkers for the disease; possible targets for the inhibition of growth and invasion by the neoplastic cells have been suggested. The significance of ncRNAs in lung cancer, bladder cancer, kidney cancer, and melanoma has been amply investigated with important results. Recently, the role of long non-coding RNAs (lncRNAs) has also been included in cancer studies. Studies on the relation between endometrial cancer (EC) and ncRNAs, such as small ncRNAs or micro RNAs (miRNAs), transfer RNAs (tRNAs), ribosomal RNAs (rRNAs), antisense RNAs (asRNAs), small nuclear RNAs (snRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), competing endogenous RNAs (ceRNAs), lncRNAs, and long intergenic ncRNAs (lincRNAs) have been published. The recent literature produced in the last three years was extracted from PubMed by two independent readers, which was then selected for the possible relation between ncRNAs, oncogenesis in general, and EC in particular.

引用

页数：15

共 77 条

[1] Sparse feature selection for classification and prediction of metastasis in endometrial cancer
Ahsen, Mehmet Eren
Boren, Todd P.
Singh, Nitin K.
Misganaw, Burook
Mutch, David G.
Moore, Kathleen N.
Backes, Floor J.
McCourt, Carolyn K.
Lea, Jayanthi S.
Miller, David S.
White, Michael A.
Vidyasagar, Mathukumalli
[J]. BMC GENOMICS, 2017, 18
[2] Role of exogenous and endogenous hormones in endometrial cancer - Review of the evidence and research perspectives
Akhmedkhanov, A
Zeleniuch-Jacquotte, A
Toniolo, P
[J]. HUMAN FERTILITY AND REPRODUCTION: THE OOCYTE, THE EMBRYO, AND THE UTERUS, 2001, 943 : 296 - 315
[3] LEFTY2 Controls Migration of Human Endometrial Cancer Cells via Focal Adhesion Kinase Activity (FAK) and miRNA-200a
Alowayed, Nour
Salker, Madhuri S.
Zeng, Ni
Singh, Yogesh
Lang, Florian
[J]. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 39 (03) : 815 - 826
[4] [Anonymous], TUMOR BIOL
[5] [Anonymous], CANC GEN ATL
[6] miRNA Processing and Human Cancer: DICER1 Cuts the Mustard
Bahubeshi, Amin
Tischkowitz, Marc
Foulkes, William D.
[J]. SCIENCE TRANSLATIONAL MEDICINE, 2011, 3 (111)
[7] Antisense Transcript Long Noncoding RNA (lncRNA) HOTAIR is Transcriptionally Induced by Estradiol
Bhan, Arunoday
Hussain, Imran
Ansari, Khairul I.
Kasiri, Sahba
Bashyal, Aarti
Mandal, Subhrangsu S.
[J]. JOURNAL OF MOLECULAR BIOLOGY, 2013, 425 (19) : 3707 - 3722
[8] Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
Cabili, Moran N.
Trapnell, Cole
Goff, Loyal
Koziol, Magdalena
Tazon-Vega, Barbara
Regev, Aviv
Rinn, John L.
[J]. GENES & DEVELOPMENT, 2011, 25 (18) : 1915 - 1927
[9] Cavanagh, 1999, Cancer Control, V6, P354
[10] Long noncoding RNAs and the genetics of cancer
Cheetham, S. W.
Gruhl, F.
Mattick, J. S.
Dinger, M. E.
[J]. BRITISH JOURNAL OF CANCER, 2013, 108 (12) : 2419 - 2425

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