Antimicrobial activity and phytochemical characterization of Carya illinoensis

被引:32
作者
Bottari, Nathieli Bianchin [1 ,2 ]
Soares Lopes, Leonardo Quintana [1 ]
Pizzuti, Kauana [1 ]
dos Santos Alves, Camilla Filippi [3 ]
Correa, Marcos Saldanha [1 ]
Bolzan, Leandro Perger [1 ]
Zago, Adriana [2 ]
Vaucher, Rodrigo de Almeida [1 ]
Boligon, Aline Augusti [4 ]
Giongo, Janice Luehring [5 ]
Baldissera, Matheus Dellamea [3 ]
Vianna Santos, Roberto Christ [3 ]
机构
[1] Ctr Univ Franciscano, Lab Microbiol Res, Santa Maria, RS, Brazil
[2] Ctr Univ Franciscano, Lab Pharmacognosy, Santa Maria, RS, Brazil
[3] Univ Fed Santa Maria, Lab Oral Microbiol Res, Santa Maria, RS, Brazil
[4] Univ Fed Santa Maria, Lab Phytochem, Santa Maria, RS, Brazil
[5] Univ Reg lntegrada Alto Uruguai URI, Lab Pharmaceut Technol, Santiago, RS, Brazil
关键词
C; illinoensis; Antimicrobial activity; Germinal tube; Phenols; Flavonoids; CANDIDA-ALBICANS; JUGLANS-REGIA; ANTIOXIDANT; IDENTIFICATION;
D O I
10.1016/j.micpath.2017.01.037
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Carya illinoensis is a widespread species, belonging to the Juglandaceae family, commonly known as Pecan. Popularly, the leaves have been used in the treatment of smoking as a hypoglycemic, cleansing, astringent, keratolytic, antioxidant, and antimicrobial agent. The following research aimed to identify for the first time the phytochemical compounds present in the leaves of C. illinoensis and carry out the determination of antimicrobial activity of aqueous and ethanolic extracts. The antimicrobial activity was tested against 20 microorganisms by determining the minimum inhibitory concentration (MIC). Phenolic acids (gallic acid and ellagic acid), flavonoids (rutin), and tannins (catechins and epicatechins) were identified by HPLC-DAD and may be partially responsible for the antimicrobial activity against Gram-positive, Gram-negative, and yeast. The results showed MIC values between 25 mg/mL and 0.78 mg/mL. The extracts were also able to inhibit the production of germ tubes by Candida albicans. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:190 / 195
页数:6
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