Online Theta Frequency Transcranial Alternating Current Stimulation for Cognitive Remediation in Schizophrenia A Case Report and Review of Literature

被引:25
作者
Sreeraj, Vanteemar S. [1 ]
Shivakumar, Venkataram [1 ]
Sowmya, Selvaraj [1 ]
Bose, Anushree [1 ]
Nawani, Hema [1 ]
Narayanaswamy, Janardhanan C. [1 ]
Venkatasubramanian, Ganesan [1 ]
机构
[1] Natl Inst Mental Hlth & Neurosci, Dept Psychiat, WISER Program, Bengaluru, India
关键词
tACS; schizophrenia; online; neuromodulation; working memory; NEURAL OSCILLATIONS; WORKING-MEMORY; TACS; HALLUCINATIONS; ALPHA;
D O I
10.1097/YCT.0000000000000523
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Transcranial alternating current stimulation (tACS), a noninvasive brain stimulation technique that uses low-intensity alternating current, has been postulated to be a potential therapeutic option in treating the cognitive deficits in schizophrenia. Transcranial alternating current stimulation synchronizes the neural oscillations to the applied stimulation frequency in the stimulated cortical regions. In this report, we have reviewed the literature pertinent to the clinical application of tACS in psychiatric disorders; in addition, we have described the clinical use of online theta tACS in a schizophrenia patient with cognitive deficits. Online theta tACS led to improvement in working memory, attention, processing speed, and emotional processing. The beneficial effect of tACS persisted during reassessment of the patient after 50 days. Transcranial alternating current stimulation, given its noninvasiveness, safety, and ease of administration, has the potential to ameliorate cognitive deficits in neuropsychiatric disorders like schizophrenia.
引用
收藏
页码:139 / 143
页数:5
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