Synthesis, structural and conformational study of some amides derived from N-methylpiperazine

被引：18

作者：

Iriepa, I. ^{[1
]}

Madrid, A. I.

Galvez, E.

Bellanato, J.

机构：

[1] Univ Alcala de Henares, Dept Quim Organ, Madrid, Spain

[2] CSIC, Inst Estructura Mat, E-28006 Madrid, Spain

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2006年 / 787卷 / 1-3期

关键词：

N-methylpiperazine; amides; infrared spectroscopy; NMR spectroscopy; conformational analysis;

D O I：

10.1016/j.molstruc.2005.10.025

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Some amides (1-6) derived from N-methylpiperazine were synthesized and studied by IR, H-1 and C-13 NMR spectroscopy. In CDCl3 solution, at room temperature, a fast interconversion of the piperazine ring with the N-CH3 group in equatorial position can be proposed. alpha,beta-unsaturated compounds 4 and 5 adopt in liquid state and in solution (CCl4, CCl2=CCl2, CDCl3) both s-cis and s-trans conformations. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：8 / 13

页数：6

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