α,β-Diaryl unsaturated ketones via palladium-catalyzed ring-opening of cyclopropenones with organoboronic acids

被引：29

作者：

Shan, Lidong ^{[1
]}

Wu, Ge ^{[2
]}

Liu, Miaochang ^{[1
]}

Gao, Wenxia ^{[1
]}

Ding, Jinchang ^{[1
]}

Huang, Xiaobo ^{[1
]}

Wu, Huayue ^{[1
]}

机构：

[1] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China

[2] Wenzhou Med Univ, Sch Pharmaceut Sci, Wenzhou 325035, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2018年 / 5卷 / 10期

基金：

中国国家自然科学基金;

关键词：

C BOND-CLEAVAGE; TERT-CYCLOBUTANOLS; CHALCONE DERIVATIVES; CONJUGATE ADDITION; OXYGEN ATMOSPHERE; ARYLATION; CHLORIDES; 1,4-ADDITION; EPOXIDES; MILD;

D O I：

10.1039/c8qo00241j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed ring-opening acylation of cyclopropenones with organoboronic acids at room temperature has been developed. Both arylboronic acids and vinylboronic acids are viable in this acylation reaction, providing a new protocol to synthesise ,-diaryl unsaturated ketones with good yields and excellent stereospecificity. Preliminary mechanistic studies indicated that a vinylpalladium intermediate was generated in this procedure.

引用

页码：1651 / 1654

页数：4