α,β-Diaryl unsaturated ketones via palladium-catalyzed ring-opening of cyclopropenones with organoboronic acids

被引：29
作者：
Shan, Lidong [1 ]
Wu, Ge [2 ]
Liu, Miaochang [1 ]
Gao, Wenxia [1 ]
Ding, Jinchang [1 ]
Huang, Xiaobo [1 ]
Wu, Huayue [1 ]
机构：
[1] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China
[2] Wenzhou Med Univ, Sch Pharmaceut Sci, Wenzhou 325035, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2018年 / 5卷 / 10期
基金：
中国国家自然科学基金;
关键词：
C BOND-CLEAVAGE; TERT-CYCLOBUTANOLS; CHALCONE DERIVATIVES; CONJUGATE ADDITION; OXYGEN ATMOSPHERE; ARYLATION; CHLORIDES; 1,4-ADDITION; EPOXIDES; MILD;
D O I：
10.1039/c8qo00241j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed ring-opening acylation of cyclopropenones with organoboronic acids at room temperature has been developed. Both arylboronic acids and vinylboronic acids are viable in this acylation reaction, providing a new protocol to synthesise ,-diaryl unsaturated ketones with good yields and excellent stereospecificity. Preliminary mechanistic studies indicated that a vinylpalladium intermediate was generated in this procedure.
引用
收藏
页码：1651 / 1654
页数：4
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