Hypoxia in head and neck cancer

被引：71
作者：
Isa, A. Y.
Ward, T. H.
West, C. M. L.
Slevin, N. J.
Homer, J. J.
机构：
[1] Christie Hosp, Dept Clin Oncol, Manchester, Lancs, England
[2] Paterson Inst Canc Res, Drug Dev Grp, Manchester M20 9BX, Lancs, England
[3] Univ Manchester, Acad Dept Radiat Oncol, Manchester, Lancs, England
[4] Christie Hosp, Dept Surg, Manchester, Lancs, England
[5] Manchester Royal Infirm, Univ Dept Otolaryngol Head & Neck Surg, Manchester M13 9DL, Lancs, England
来源：
BRITISH JOURNAL OF RADIOLOGY | 2006年 / 79卷 / 946期
关键词：
D O I：
10.1259/bjr/17904358
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A high level of hypoxia in solid tumours is an adverse prognostic factor for the poor outcome of cancer patients following treatment. This review describes the status of research into finding a practical method for measuring hypoxia and treating hypoxic tumours. The application of such methodology would enable the selection of head and neck cancer treatment based on an individual's tumour oxygenation status. This individualization would include the selection not only of surgery or radiotherapy, but also of novel hypoxia-modification strategies.
引用
收藏
页码：791 / 798
页数：8
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