Novel method for efficient aerobic oxidation of silyl ethers to carbonyl compounds catalyzed with N-hydroxyphthalimide (NHPI) and lipophilic Co(II) complexes

被引：26
作者：
Karimi, B
Rajabi, J
机构：
[1] IASBS, Dept Chem, Zanjan, Iran
[2] Inst Fundamental Res, Tehran, Iran
来源：
ORGANIC LETTERS | 2004年 / 6卷 / 17期
关键词：
D O I：
10.1021/ol049294+
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this work, a new method for highly efficient and selective oxidative deprotection of a variety of structurally diverse trimethylsilyl (TMS) and tert-butyidimethylsilyl (TBS) ethers using molecular oxygen in the presence of N-hydroxyphthalimide (NHPI) and various types of Co(II) complexes is reported. As a result of the relatively neutral reaction medium, acid-sensitive functional groups such as phenolic TBS ethers survived intact under the presented reaction conditions.
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页码：2841 / 2844
页数：4
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