Levodopa therapeutics for Parkinson's disease: new developments

被引:17
作者
LeWitt, Peter A. [1 ,2 ]
机构
[1] Wayne State Univ, Sch Med, Dept Neurol, Detroit, MI 48201 USA
[2] Henry Ford Hosp, Dept Neurol, Detroit, MI 48202 USA
关键词
Levodopa; Anti-parkinsonian therapy; New delivery system; L-DOPA; MOTOR FLUCTUATIONS; PHARMACOKINETICS; PROGRESSION; INITIATION; REPLACEMENT; DYSKINESIAS; CARBIDOPA; SYSTEM; TRIAL;
D O I
10.1016/S1353-8020(09)70009-4
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Levodopa serves as the gold standard of anti-parkinsonian therapy and nearly every patient with Parkinson's disease eventually receives this drug. To improve upon levodopa therapy, several forms of treatment have been devised to augment its actions. and new delivery systems are under development. This new research offers promise for improving outcomes with this highly effective therapy. (c) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:S31 / S34
页数:4
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