Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties

被引：84

作者：

Ghadban, Ali ^{[1
,2
]}

Ahmed, Anansa S. ^{[1
]}

Ping, Yuan ^{[1
,2
]}

Ramos, Ricardo ^{[1
,2
]}

Arfin, Najmul ^{[1
,2
]}

Cantaert, Bram ^{[1
,2
]}

Ramanujan, Raju V. ^{[1
]}

Miserez, Ali ^{[1
,2
,3
]}

机构：

[1] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore

[2] Nanyang Technol Univ, Ctr Biomimet Sensor Sci, Singapore 637553, Singapore

[3] Nanyang Technol Univ, Sch Biol Sci, Singapore 637551, Singapore

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 04期

基金：

新加坡国家研究基金会;

关键词：

MECHANISM; NETWORKS;

D O I：

10.1039/c5cc08617e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have developed pH- and magnetic-responsive hydrogels that are stabilized by both covalent bonding and catechol/Fe3+ ligands. The viscoelastic properties of the gels are regulated by the complexation valence and can be used to tune drug release profiles. The stable incorporation of magnetic nanoparticles further expands control over the mechanical response and drug release, in addition to providing magnetic stimuli-responsivity to the gels.

引用

页码：697 / 700

页数：4

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