Fluid lamellar keratoplasty in keratoconus

Objective: The authors evaluated the efficacy of the modified technique of fluid deep lamellar keratoplasty in keratoconus. Design: Noncomparative case series. Participants: Twenty-six eyes of 25 patients with moderate to advanced keratoconus were included. Fourteen males and 11 females with age range of 16 to 37 years. Intervention: Deep lamellar keratoplasty aided by intrastromal injection of balanced salt solution to facilitate corneal dissection down to Descemet's membrane, Full-thickness graft devoid of endothelium and Descemet's membrane was then sutured in place. Main Outcome Measures: Spectacle-corrected visual acuity, slit-lamp biomicroscopy, corneal topography, and ocular tension. Results: Two cases (8.4%) were converted to penetrating keratoplasty because of intraoperative perforation, Of the 24 successful cases, 19 eyes (79%) achieved >20/50 at 3 months and 21 (87.5%) achieved >20/40 at 6 months. Twenty-three eyes (95.8%) were 20/30 or better 1 year after suture removal. Only one eye (4.2%) had interface irregular astigmatism corrected by contact lens to 20/40. Conclusions: Fluid deep lamellar keratoplasty is a safe and effective procedure, especially in bilateral keratoconus, because it has no rejection complication. However, it is technically difficult with slow visual rehabilitation. Ophthalmology 2000;107:76-80 (C) 2000 by the American Academy of Ophthalmology.