Uptake of injected PCBs from the yolk by the developing chicken embryo

In this study, PCB uptake by the developing chicken embryo was measured after injection of two different doses of Aroclor 1254 before incubation. It was shown that 2% of the injected PCBs was absorbed on day 13, and this increased exponentially to 18% at day 19. This exponential increase could be described by a similar model for both low and high injection doses. Differences in injection dose resulted in corresponding differences in concentration in the embryos. Lipid corrected concentrations in the embryo were stable through development from day 13 up to day 19 and could be predicted from injection doses by using a conversion factor of 0.15 g(-1). (C) 2002 Elsevier Science Ltd. All rights reserved.