Nicotine Exposure, Blood Pressure, and Inflammation in Tobacco Smokers and Chewers in a Rural Community in Nepal

被引：3
作者：
Pandey, Arti S. [1 ]
Shreevastva, Naveen K. [1 ]
Neupane, Durga P. [1 ]
机构：
[1] Kathmandu Med Coll, Dept Biochem, Duwakot, Bhaktapur, Nepal
来源：
SUBSTANCE USE & MISUSE | 2014年 / 49卷 / 07期
关键词：
tobacco; blood pressure; nicotine metabolites; cotinine; differential cell counts; CIGARETTE-SMOKING; CELL COUNT; HYPERTENSION; DISPOSITION; ASSOCIATION; METABOLISM;
D O I：
10.3109/10826084.2014.880483
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
Tobacco consumption is high amongst the people of Nepal. This study was carried out in 2011 in a rural community of Nepal, to compare pathological parameters associated with tobacco use in relation to nicotine metabolism between smokers, chewers, and a control group. A total of 216 volunteers provided blood and urine samples for testing nicotine metabolites, C-reactive protein, and cell counts. Data were analyzed using ANOVA, correlation, and t-tests using STATA. Differences in blood pressure amongst the groups indicate a role of smoking in preventing a rise in BP with age, likely attributable to a different mechanism of metabolism of tobacco constituents.
引用
收藏
页码：798 / 803
页数：6
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