Human Th17 cells in infection and autoimmunity

被引：93
|
作者：
Sallusto, Federica [1 ]
Lanzavecchia, Antonio [1 ]
机构：
[1] Biomed Res Inst, CH-6500 Bellinzona, Switzerland
来源：
MICROBES AND INFECTION | 2009年 / 11卷 / 05期
关键词：
Human Th17; Memory T cell; Chemokine receptor; GROWTH-FACTOR-BETA; HUMAN T-CELLS; HUMAN AIRWAY EPITHELIUM; TGF-BETA; INTERLEUKIN-17; PRODUCTION; DIFFERENTIAL REGULATION; DENDRITIC CELLS; UP-REGULATION; IFN-GAMMA; T(H)17;
D O I：
10.1016/j.micinf.2009.04.004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
IL-17-producing T cells (Th17) have been identified in mice as a distinct lineage of CD4(+) T helper cells. Since their discovery, efforts have been made in characterizing human Th17 cells and the factors involved in their differentiation and in understanding the role these cells play in protective immunity and autoimmune diseases. (C) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：620 / 624
页数：5
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