Monitoring of endocrine disruptors by capillary electrophoresis amperometric detector

被引:16
作者
Ha, Kon [2 ]
Joo, Gi-sung [2 ]
Jha, Sandeep Kumar [2 ]
Kim, Yong-Sang [1 ,2 ]
机构
[1] Myongji Univ, Dept Elect Engn, Yongin 449728, Gyeonggi, South Korea
[2] Myongji Univ, Dept Nano Sci Engn, Yongin 449728, Gyeonggi, South Korea
关键词
Capillary electrophoresis; Styrofoam; Endocrine disruptor; Bisphenol A (BPA); Amperometry; Prussian blue (PB); BISPHENOL-A; IN-VITRO; BIOSENSOR;
D O I
10.1016/j.mee.2009.02.025
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A capillary electrophoresis amperometric detector was fabricated using Prussian blue (PB) modified indium tin oxide (ITO) electrode and twisted microchannel configuration. These devices were used for detection of endocrine disruptors, such as bisphenol A (BPA) and butylphenol after their effective separation in microchannel. The microchip had a limit of detection (LOD) as low as 59 nM for analytes. This approach was further applied in detection of these contaminants in Styrofoam food container used in many East Asian countries, such as Korea and China, for packaging of instant noodle, a popular fast food. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:1407 / 1410
页数:4
相关论文
共 19 条
[1]  
Bai XX, 2000, ELECTROANAL, V12, P535, DOI 10.1002/(SICI)1521-4109(200005)12:7<535::AID-ELAN535>3.0.CO
[2]  
2-Y
[3]   Determination of bisphenol A in food-simulating liquids using LCED with a chemically modified electrode [J].
D'Antuono, A ;
Dall'Orto, VC ;
Lo Balbo, A ;
Sobral, S ;
Rezzano, I .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2001, 49 (03) :1098-1101
[4]  
Ha K, 2008, J NEW MAT ELECTR SYS, V11, P55
[5]   Amphibians as a model to study endocrine disruptors: II. Estrogenic activity of environmental chemicals in vitro and in vivo [J].
Kloas, W ;
Lutz, I ;
Einspanier, R .
SCIENCE OF THE TOTAL ENVIRONMENT, 1999, 225 (1-2) :59-68
[6]   Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons [J].
Le, Hoa H. ;
Carlson, Emily M. ;
Chua, Jason P. ;
Belcher, Scott M. .
TOXICOLOGY LETTERS, 2008, 176 (02) :149-156
[7]   Modulatory effect of environmental endocrine disruptors on N-ras oncogene expression in the hermaphroditic fish, Kryptolebias marmoratus [J].
Lee, Young-Mi ;
Raisuddin, Sheikh ;
Rhee, Jae-Sung ;
Ki, Jang-Seu ;
Kim, Il-Chan ;
Lee, Jae-Seong .
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2008, 147 (03) :299-305
[8]   Mechanisms and risk of chemically induced aneuploidy in mammalian germ cells [J].
Pacchierotti, Francesca ;
Ranaldi, Roberto .
CURRENT PHARMACEUTICAL DESIGN, 2006, 12 (12) :1489-1504
[9]   Sensor and biosensor preparation, optimisation and applications of Prussian Blue modified electrodes [J].
Ricci, F ;
Palleschi, G .
BIOSENSORS & BIOELECTRONICS, 2005, 21 (03) :389-407
[10]   Degradation of bisphenol-A (BPA) in the presence of reactive oxygen species and its acceleration by lipids and sodium chloride [J].
Sajiki, J ;
Yonekubo, J .
CHEMOSPHERE, 2002, 46 (02) :345-354