DNA Content, Cell Size, and Cell Senescence

被引：16

作者：

Veitia, Reiner A. ^{[1
,2
]}

机构：

[1] Univ Paris Diderot, Inst Jacques Monod, Paris, France

[2] Univ Paris Diderot, Paris, France

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2019年 / 44卷 / 08期

关键词：

YEAST; LEADS;

D O I：

10.1016/j.tibs.2019.04.013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A recent study assessed the impact of cell size on various cell properties. Oversized yeast cells display slow cell division, cytoplasmic dilution, and transcriptomic and proteomic alterations. It highlights commonalities between aging yeast and mammalian cells, suggesting the existence of a range of DNA content: cell volume ratio ensuring optimal function.

引用

页码：645 / 647

页数：4

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