Development of novel anticancer drugs which inhibit E2F transcription factor

被引：2

作者：

Yoshida, T

Sakai, Y

Mizukami, T

机构：

[1] Tokyo Research Laboratories, Kyowa Hakko Kogyo Co. LTD.

来源：

NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY | 1997年 / 71卷 / 05期

关键词：

E2F; anticancer drug; transcription factor; cell cycle; natural product;

D O I：

10.1271/nogeikagaku1924.71.516

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：516 / 519

页数：4

共 20 条

[1]

AKIYAMA T, IN PRESS CANC RES

[2] MITHRAMYCIN INHIBITS SP1 BINDING AND SELECTIVELY INHIBITS TRANSCRIPTIONAL ACTIVITY OF THE DIHYDROFOLATE-REDUCTASE GENE INVITRO AND INVIVO [J].

BLUME, SW ;

SNYDER, RC ;

RAY, R ;

THOMAS, S ;

KOLLER, CA ;

MILLER, DM .

JOURNAL OF CLINICAL INVESTIGATION, 1991, 88 (05) :1613-1621

[3] Adriamycin-induced DNA adducts inhibit the DNA interactions of transcription factors and RNA polymerase [J].

Cutts, SM ;

Parsons, PG ;

Sturm, RA ;

Phillips, DR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (10) :5422-5429

[4]

DOBROWOLSKI SF, 1994, ONCOGENE, V9, P2605

[5] E2F-1 functions in mice to promote apoptosis and suppress proliferation [J].

Field, SJ ;

Tsai, FY ;

Kuo, F ;

Zubiaga, AM ;

Kaelin, WG ;

Livingston, DM ;

Orkin, SH ;

Greenberg, ME .

CELL, 1996, 85 (04) :549-561

[6] SPECIFIC-INHIBITION OF FORMATION OF TRANSCRIPTION COMPLEXES BY A CALICHEAMICIN OLIGOSACCHARIDE - A PARADIGM FOR THE DEVELOPMENT OF TRANSCRIPTIONAL ANTAGONISTS [J].

HO, SN ;

BOYER, SH ;

SCHREIBER, SL ;

DANISHEFSKY, SJ ;

CRABTREE, GR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (20) :9203-9207

[7]

HOROWITZ M, 1991, CELL, V65, P1053

[8] Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function [J].

Ishizaki, J ;

Nevins, JR ;

Sullenger, BA .

NATURE MEDICINE, 1996, 2 (12) :1386-1389

[9] ONCOGENIC CAPACITY OF THE E2F1 GENE [J].

JOHNSON, DG ;

CRESS, WD ;

JAKOI, L ;

NEVINS, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (26) :12823-12827

[10] EXPRESSION OF TRANSCRIPTION FACTOR E2F1 INDUCES QUIESCENT CELLS TO ENTER S-PHASE [J].

JOHNSON, DG ;

SCHWARZ, JK ;

CRESS, WD ;

NEVINS, JR .

NATURE, 1993, 365 (6444) :349-352

← 1 2 →