Adult-onset idiopathic hypogonadotropic hypogonadism due to isolated pituitary gonadotropin deficiency

被引：2

作者：

Suzuki, F

Shimizu, C

Umetsu, M

Nagai, S

Takeuchi, J

Endo, M

Miyoshi, H

Yoshioka, N

Kubo, M

Koike, T

机构：

[1] Hokkaido Univ, Grad Sch Med, Dept Med 2, Kita Ku, Sapporo, Hokkaido 0608638, Japan

[2] Hokkaido Univ, Hlth Adm Ctr, Sapporo, Hokkaido, Japan

来源：

INTERNAL MEDICINE | 2004年 / 43卷 / 07期

关键词：

isolated; erectile dysfunction; gynecomastia;

D O I：

10.2169/internalmedicine.43.571

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 25-year-old Japanese man with adult-onset idiopathic hypogonadotropic hypogonadism is reported. He had been delivered normally, had normal puberty, and experienced erectile dysfunction at age 24 years. Brain MRI revealed no abnormal findings and endocrinological data supported the diagnosis of isolated gonadotropin deficiency. Although most patients with idiopathic hypogonadotropic hypogonadism have a hypothalamic dysfunction, the lesion in this case may be considered to be in the pituitary since repetitive GnRH loading failed to increase serum LH and FSH.

引用

页码：571 / 574

页数：4

共 12 条

[1]

Achermann JC, 2001, J PEDIATR ENDOCR MET, V14, P3

[2]

BARKAN AL, 1985, NEW ENGL J MED, V312, P1535

[3] Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism [J].