A highly selective and sensitive fluorescent turn-on Al3+ chemosensor in aqueous media and living cells: experimental and theoretical studies

被引：55
作者：
Hwang, In Hong [1 ,2 ]
Choi, Ye Won [1 ,2 ]
Kim, Kyung Beom [1 ,2 ]
Park, Gyeong Jin [1 ,2 ]
Lee, Jae Jun [1 ,2 ]
LeTuyen Nguyen [3 ,4 ]
Noh, Insup [3 ,4 ]
Kim, Cheal [1 ,2 ]
机构：
[1] Seoul Natl Univ Sci & Technol, Dept Fine Chem, Seoul 139743, South Korea
[2] Seoul Natl Univ Sci & Technol, Dept Interdisciplinary Bio IT Mat, Seoul 139743, South Korea
[3] Seoul Natl Univ Sci & Technol, Dept Chem & Biomol Engn, Seoul 139743, South Korea
[4] Seoul Natl Univ Sci & Technol, Convergence Program Biomed Engn & Biomat, Seoul 139743, South Korea
来源：
NEW JOURNAL OF CHEMISTRY | 2016年 / 40卷 / 01期
基金：
新加坡国家研究基金会;
关键词：
SCHIFF-BASE FLUORESCENCE; COLORIMETRIC SENSOR; METAL-IONS; ALUMINUM; PROBE; AL(III); CR3+; RECOGNITION; COMPLEX; ZN(II);
D O I：
10.1039/c5nj02334c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly selective and sensitive fluorescent chemosensor (1) based on a 2-aminobenzoic acid Schiff base has been synthesized in one step. The binding properties of 1 with metal ions were investigated by fluorescence, UV-vis, H-1 NMR and electrospray ionization mass spectra. This sensor exhibited enhanced fluorescence in the presence of Al3+ in aqueous solution and aka in living cells. The sensing mechanism of 1 toward Al3+ was explained by DFT/TDDFT calculations. The binding constant was determined to be 3.1 x 10(8) M-1 which is one of the highest binding affinities among such simple Schiff bases for Al3+ in buffer solution. The calibration curve for the analytical performance of Al3+ was found to be linear over a concentration range with a very low detection limit of 290 nM (3 sigma).
引用
收藏
页码：171 / 178
页数：8
相关论文
共 87 条
  • [1] A cyanobiphenyl containing fluorescence "turn on" sensor for Al3+ ion in CH3CN-water
    Alici, Onder
    Erdemir, Serkan
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2015, 208 : 159 - 163
  • [2] A naphthalene exciplex based Al3+ selective on-type fluorescent probe for living cells at the physiological pH range: experimental and computational studies
    Banerjee, Arnab
    Sahana, Animesh
    Das, Sudipta
    Lohar, Sisir
    Guha, Subarna
    Sarkar, Bidisha
    Mukhopadhyay, Subhra Kanti
    Mukherjee, Asok K.
    Das, Debasis
    [J]. ANALYST, 2012, 137 (09) : 2166 - 2175
  • [3] Fast root growth responses, root exudates, and internal detoxification as clues to the mechanisms of aluminium toxicity and resistance: a review
    Barcelo, J
    Poschenrieder, C
    [J]. ENVIRONMENTAL AND EXPERIMENTAL BOTANY, 2002, 48 (01) : 75 - 92
  • [4] Quantum calculation of molecular energies and energy gradients in solution by a conductor solvent model
    Barone, V
    Cossi, M
    [J]. JOURNAL OF PHYSICAL CHEMISTRY A, 1998, 102 (11) : 1995 - 2001
  • [5] DENSITY-FUNCTIONAL THERMOCHEMISTRY .3. THE ROLE OF EXACT EXCHANGE
    BECKE, AD
    [J]. JOURNAL OF CHEMICAL PHYSICS, 1993, 98 (07) : 5648 - 5652
  • [6] Aluminium speciation in relation to aluminium bioavailability, metabolism and toxicity
    Berthon, G
    [J]. COORDINATION CHEMISTRY REVIEWS, 2002, 228 (02) : 319 - 341
  • [7] Metal-induced self-assembly of a pyrene-tethered hydroxamate ligand for the generation of multichromophoric supramolecular systems. The pyrene excimer as switch for iron(III)-driven intramolecular fluorescence quenching
    Bodenant, B
    Fages, F
    Delville, MH
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (30) : 7511 - 7519
  • [8] Fluorescent sensors for Zn2+ based on a fluorescein platform:: Synthesis, properties and intracellular distribution
    Burdette, SC
    Walkup, GK
    Spingler, B
    Tsien, RY
    Lippard, SJ
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (32) : 7831 - 7841
  • [9] A Highly Selective Chemosensor for AI(III) and Zn(II) and Its Coordination with Metal Ions
    Cao, Wei
    Zheng, Xiang-Jun
    Sun, Ji-Ping
    Wong, Wing-Tak
    Fang, De-Cai
    Zhang, Jia-Xin
    Jin, Lin-Pei
    [J]. INORGANIC CHEMISTRY, 2014, 53 (06) : 3012 - 3021
  • [10] A turn-on and reversible Schiff base fluorescence sensor for Al3+ ion
    Chen, Chang-Hung
    Liao, De-Jhong
    Wan, Chin-Feng
    Wu, An-Tai
    [J]. ANALYST, 2013, 138 (09) : 2527 - 2530
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