Bone Marrow Transplantation for Acquired Severe Aplastic Anemia

被引：20

作者：

Bacigalupo, Andrea ^{[1
,2
]}

机构：

[1] IRCCS San Martino, Div Hematol, I-16132 Genoa, Italy

[2] IRCCS San Martino, Bone Marrow Transplant Unit, I-16132 Genoa, Italy

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2014年 / 28卷 / 06期

关键词：

Acquired severe aplastic anemia; Bone marrow transplantation; Unrelated donors; Graft-versus-host disease; STEM-CELL TRANSPLANTATION; SIBLING DONOR TRANSPLANTS; TERM-FOLLOW-UP; PERIPHERAL-BLOOD; HEMATOPOIETIC CHIMERISM; UNRELATED DONORS; GRAFT-REJECTION; PATIENTS OLDER; FLUDARABINE; CYCLOPHOSPHAMIDE;

D O I：

10.1016/j.hoc.2014.08.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This article addresses current transplant options for patients with acquired severe aplastic anemia (SAA). This discussion includes ongoing progress in the use of SAA in the setting of unrelated donor transplants, which now provide outcomes similar, though still not identical, to HLA-identical sibling transplants. Recent data on stem cell source, conditioning regimens, and graft-versus-host disease prophylaxis are outlined. Other donor types such as cord blood and haploidentical mismatched family donors are also discussed.

引用

页码：1145 / +

页数：13

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