Novel processing of bioglass ceramics from silicone resins containing micro- and nano-sized oxide particle fillers

被引:14
作者
Fiocco, L. [1 ]
Bernardo, E. [1 ]
Colombo, P. [1 ,4 ]
Cacciotti, I. [2 ]
Bianco, A. [2 ]
Bellucci, D. [3 ]
Sola, A. [3 ]
Cannillo, V. [3 ]
机构
[1] Univ Padua, Dipartimento Ingn Ind, I-35131 Padua, Italy
[2] Univ Roma Tor Vergata, Dipartimento Ingn Ind, INSTM UdR Roma Tor Vergata, I-00133 Rome, Italy
[3] Univ Modena & Reggio Emilia, Dipartimento Ingn E Ferrari, I-41125 Modena, Italy
[4] Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16801 USA
关键词
polymer-derived ceramics; bioglasses; glass-ceramics; porous scaffolds; bioactivity; POLYMER-DERIVED CERAMICS; IN-VITRO BIOACTIVITY; PRECERAMIC POLYMERS; BONE-FORMATION; GLASS; HYDROXYAPATITE; OSTEOBLASTS; SCAFFOLDS; PROLIFERATION; BIOCERAMICS;
D O I
10.1002/jbm.a.34918
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Highly porous scaffolds with composition similar to those of 45S5 and 58S bioglasses were successfully produced by an innovative processing method based on preceramic polymers containing micro- and nano-sized fillers. Silica from the decomposition of the silicone resins reacted with the oxides deriving from the fillers, yielding glass ceramic components after heating at 1000 degrees C. Despite the limited mechanical strength, the obtained samples possessed suitable porous architecture and promising biocompatibility and bioactivity characteristics, as testified by preliminary in vitro tests. (C) 2013 Wiley Periodicals, Inc.
引用
收藏
页码:2502 / 2510
页数:9
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