Zinc fingers poke zebrafish, cause thrombosis!

被引：0

作者：

Jagadeeswaran, Pudur ^{[1
]}

机构：

[1] Univ N Texas, Denton, TX 76203 USA

来源：

BLOOD | 2014年 / 124卷 / 01期

关键词：

D O I：

10.1182/blood-2014-05-574319

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this issue of Blood, Liu et al describe the creation of a null mutation for the antithrombin III gene (at3) in zebrafish by using zinc finger nuclease technology.(1)

引用

页码：9 / 10

页数：2

共 6 条

[1] Zinc finger-based knockout punches for zebrafish genes [J].

Ekker, Stephen C. .

ZEBRAFISH, 2008, 5 (02) :121-123

[2] Genetic analysis of hemostasis and thrombosis using vascular occlusion [J].

Gregory, M ;

Hanumanthaiah, R ;

Jagadeeswaran, P .

BLOOD CELLS MOLECULES AND DISEASES, 2002, 29 (03) :286-295

[3] Analysis of blood coagulation in the zebrafish [J].

Jagadeeswaran, P ;

Sheehan, JP .

BLOOD CELLS MOLECULES AND DISEASES, 1999, 25 (15) :239-249

[4] Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function [J].

Liu, Yang ;

Kretz, Colin A. ;

Maeder, Morgan L. ;

Richter, Catherine E. ;

Tsao, Philip ;

Vo, Andy H. ;

Huarng, Michael C. ;

Rode, Thomas ;

Hu, Zhilian ;

Mehra, Rohit ;

Olson, Steven T. ;

Joung, J. Keith ;

Shavit, Jordan A. .

BLOOD, 2014, 124 (01) :142-150

[5] Disruption of hemoglobin oxygen transport does not impact oxygen-dependent physiological processes in developing embryos of zebra fish (Danio rerio) [J].

Pelster, B ;

Burggren, WW .

CIRCULATION RESEARCH, 1996, 79 (02) :358-362

[6] The effects of anticoagulants on hematological indices and blood cell morphology of common carp (Cyprinus carpio L.) [J].

Walencik, Jacek ;

Witeska, Malgorzata .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2007, 146 (03) :331-335

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