GLOMERULAR DISEASE The search goes on: suPAR is not the elusive FSGS factor

被引:13
作者
Deegens, Jeroen K. [1 ]
Wetzels, Jack E. [1 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Dept Nephrol, NL-6500 HB Nijmegen, Netherlands
关键词
FOCAL SEGMENTAL GLOMERULOSCLEROSIS; UROKINASE RECEPTOR; SERUM SUPAR; KIDNEY;
D O I
10.1038/nrneph.2014.113
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
New research indicates that intact soluble urokinase plasminogen activator receptor (suPAR) does not induce albuminuria in mice. These data corroborate the most recent clinical findings, showing that intact suPAR is not the plasma permeability factor responsible for recurrence of focal segmental glomerulosclerosis after renal transplantation.
引用
收藏
页码:431 / 432
页数:2
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