Sulphur-containing derivatives structurally related to fenoxycarb are potent growth inhibitors against the intracellular form of Trypanosoma cruzi

被引：7
|
作者：
Rodriguez, JB
Docampo, R
Gros, EG
机构：
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina
[2] Univ Illinois, Coll Vet Med, Dept Pathobiol, Mol Parasitol Lab, Urbana, IL 61801 USA
来源：
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2000年 / 13卷 / 03期
关键词：
Trypanosoma cruzi; amastigotes; growth inhibitors; antiparasitic agents;
D O I：
10.1016/S0924-8579(99)00125-9
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Sulphur-containing derivatives structurally related to the insect growth regulator fenoxycarb were shown to be extremely active antiproliferative agents against the amastigote form of Trypanosoma cruzi in in vitro assays. All of these drugs had previously been proved to be remarkably potent growth inhibitors against the epimastigote form of the parasite. (C) 2000 Published by Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码：215 / 218
页数：4
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