ELEVATED CHEMOKINE MRNA IN RECTAL MUCOSA IN IRRITABLE BOWEL SYNDROME; INCREASED BY GASTROINTESTINAL INFECTION BUT UNRELATED TO GUT PERMEABILITY

被引:0
|
作者
Spiller, R. C. [1 ]
Campbell, E. [1 ]
Richards, M. [1 ]
Garsed, K. [1 ]
Zaitoun, A. [1 ]
Hastings, M. [2 ]
Mahida, Y. [1 ]
Hall, I. [3 ]
Neal, K. [1 ]
Cox, J. [4 ]
Kelly, F. [4 ]
Wilde, J. [4 ]
Dukes, G. [4 ]
Whorwell, P. [2 ]
机构
[1] Univ Nottingham, Nottingham Digest Dis Ctr BRU, Nottingham NG7 2RD, England
[2] Univ S Manchester, Wythenshawe Hosp, Dept Gastroenterol, Manchester, Lancs, England
[3] Univ Nottingham, Dept Therapeut & Mol Med, Nottingham NG7 2RD, England
[4] GSK, Mol Discovery Res, Discovery Technol Grp, Harlow, Essex, England
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:A30 / A30
页数:1
相关论文
共 50 条
  • [1] Elevated Chemokine mRNA in Rectal Mucosa Following Gastrointestinal Infection and in Irritable Bowel Syndrome
    Spiller, Robin C.
    Garsed, Klara
    Cox, Joanne
    Kelly, Fiona M.
    Zaitoun, Abed M.
    Dukes, George E.
    Hastings, Margaret
    Neal, Keith R.
    Mahida, Yashwant R.
    Richards, Marguerite G.
    Hall, Ian
    Whorwell, Peter J.
    Wilde, Jonathan I.
    GASTROENTEROLOGY, 2009, 136 (05) : A105 - A106
  • [2] Increased Gastrointestinal Permeability and Gut Inflammation in Children with Functional Abdominal Pain and Irritable Bowel Syndrome
    Shulman, Robert J.
    Eakin, Michelle N.
    Czyzewski, Danita I.
    Jarrett, Monica
    Ou, Ching-Nan
    JOURNAL OF PEDIATRICS, 2008, 153 (05): : 646 - 650
  • [3] Gut permeability is affected by sex and increased in children with irritable bowel syndrome but not in functional abdominal pain
    Shulman, Robert J.
    Devaraj, Sridevi
    Heitkemper, Margaret
    NEUROGASTROENTEROLOGY AND MOTILITY, 2020, 32 (03):
  • [4] Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome
    Spiller, RC
    Jenkins, D
    Thornley, JP
    Hebden, JM
    Wright, T
    Skinner, M
    Neal, KR
    GUT, 2000, 47 (06) : 804 - 811
  • [5] Nerve growth factor content is increased in the rectal mucosa of children with diarrhea-predominant irritable bowel syndrome
    Willot, S.
    Gauthier, C.
    Patey, N.
    Faure, C.
    NEUROGASTROENTEROLOGY AND MOTILITY, 2012, 24 (08): : 734 - +
  • [6] Increased rate of irritable bowel syndrome and functional gastrointestinal disorders after Clostridium difficile infection
    Sethi, S.
    Garey, K. W.
    Arora, V.
    Ghantoji, S.
    Rowan, P.
    Smolensky, M.
    DuPont, H. L.
    JOURNAL OF HOSPITAL INFECTION, 2011, 77 (02) : 172 - 173
  • [7] Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. The confluence of increased permeability, inflammation, and pain in irritable bowel syndrome
    Camilleri, Michael
    Lasch, Karen
    Zhou, Wen
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2012, 303 (07): : G775 - G785
  • [8] Increased Gut Permeability in First-degree Relatives of Children with Irritable Bowel Syndrome or Functional Abdominal Pain
    McOmber, Mark
    Rafati, Danny
    Cain, Kevin
    Devaraj, Sridevi
    Weidler, Erica M.
    Heitkemper, Margaret
    Shulman, Robert J.
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2020, 18 (02) : 375 - +
  • [9] Rectal sensitivity and gastrointestinal symptom severity in irritable bowel syndrome (IBS): Is there a link?
    Syrous, A
    Lindstrom, L
    Lindh, A
    Bjornsson, E
    Abrahamsson, H
    Simren, M
    GASTROENTEROLOGY, 2005, 128 (04) : A110 - A110
  • [10] Gut permeability and inflammation in irritable bowel syndrome and inflammatory bowel disease: implications for pregnancy complications
    Sabra, Z.
    Kennedy, P. J.
    Moloney, G. M.
    Cryan, J. F.
    Dinan, T. G.
    Quigley, E. M. M.
    Khashan, A. S.
    Kenny, L. C.
    Clarke, G.
    NEUROGASTROENTEROLOGY AND MOTILITY, 2016, 28 : 27 - 28