Parvovirus B19 infection associated with severe aplastic anemia in an immunocompetent patient

被引：24

作者：

Yetgin, S ^{[1
]}

Çetin, M ^{[1
]}

Özyürek, E ^{[1
]}

Aslan, D ^{[1
]}

Uçkan, D ^{[1
]}

机构：

[1] Hacettepe Univ, Fac Med, Hematol Sect, Dept Pediat, TR-06100 Ankara, Turkey

来源：

PEDIATRIC HEMATOLOGY AND ONCOLOGY | 2004年 / 21卷 / 03期

关键词：

aplastic anemia; child; parvovirus B19;

D O I：

10.1080/08880010490276935

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human parvovirus B19 (PVB19) infection may cause mild pancytopenia characterized by transient and spontaneous recovery in healthy subjects. Severe aplastic anemia associated with PVB19 infection in patients without an underlying disease has been described in a number of reports. Here, a previous healthy, 10-year-old girl with severe aplastic anemia associated with PVB19 infection is described. The patient underwent bone marrow transplantation from her HLA-identical sibling resulting in complete recovery. PVB19 infection should be considered as one of the causes of aplastic anemia in patients without an underlying disease.

引用

页码：223 / 226

页数：4

共 19 条

[1]

ALTER BP, 1998, HEMATOLOGY INFANCY C, P238

[2] Haematological consequences of parvovirus B19 infection [J].

Brown, KE .

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2000, 13 (02) :245-259

[3] Glycosphingolipid expression in acute nonlymphocytic leukemia: common expression of shiga toxin and parvovirus B19 receptors on early myeloblasts [J].

Cooling, LLW ;

Zhang, DS ;

Naides, SJ ;

Koerner, TAW .

BLOOD, 2003, 101 (02) :711-721

[4] Acute liver disease and aplastic anemia associated with the persistence of B19 DNA in liver and bone marrow [J].

Dame, C ;

Hasan, C ;

Bode, U ;

Eis-Hübinger, AM .

PEDIATRIC PATHOLOGY & MOLECULAR MEDICINE, 2002, 21 (01) :25-29

[5] CHRONIC PARVOVIRUS INFECTION IN A PRESUMABLY IMMUNOLOGICALLY HEALTHY WOMAN [J].

FADEN, H ;

GARY, GW ;

ANDERSON, LJ .

CLINICAL INFECTIOUS DISEASES, 1992, 15 (04) :595-597

[6] PARVOVIRUS B19 AS A CAUSE OF ACQUIRED CHRONIC PURE RED-CELL APLASIA [J].

FRICKHOFEN, N ;

CHEN, ZJ ;

YOUNG, NS ;

COHEN, BJ ;

HEIMPEL, H ;

ABKOWITZ, JL .

BRITISH JOURNAL OF HAEMATOLOGY, 1994, 87 (04) :818-824

[7]

HASLE H, 1994, AM J PEDIAT HEMATOL, V16, P329

[8]

Heegaard ED, 1997, HAEMATOLOGICA, V82, P402

[9] PARVOVIRUS - THE EXPANDING SPECTRUM OF DISEASE [J].

HEEGAARD, ED ;

HORNSLETH, A .

ACTA PAEDIATRICA, 1995, 84 (02) :109-117

[10] Transient pancytopenia preceding acute lymphoblastic leukaemia (pre-ALL) precipitated by parvovirus B19 [J].

Heegaard, ED ;

Madsen, HO ;

Schmiegelow, K .

BRITISH JOURNAL OF HAEMATOLOGY, 2001, 114 (04) :810-813

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